Tyrosine Radical Formation in the Reaction of Wild Type and Mutant Cytochrome P450cam with Peroxy Acids
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چکیده
منابع مشابه
Molecular Docking and In Silico Study of Denileukin Diftitox: Comparison of Wild Type With C519S-Mutant
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15 صفحه اولDirect evidence for a tyrosine radical in the reaction of cytochrome c oxidase with hydrogen peroxide.
Cytochrome c oxidase (COX) catalyzes the reduction of oxygen to water, a process which is accompanied by the pumping of four protons across the membrane. Elucidation of the structures of intermediates in these processes is crucial for understanding the mechanism of oxygen reduction. In the work presented here, the reaction of H(2)O(2) with the fully oxidized protein at pH 6.0 has been investiga...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m307884200